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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1993-1-27
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pubmed:abstractText |
In a cross-sectional study, 65 workers in the chemical industry with exposure to platinum salts were investigated with regard to the prevalence to allergic respiratory tract diseases. A respiratory questionnaire, a skin-prick test with K2PtCl6 and environmental allergens, determination of total IgE, platinum-specific IgE and histamine release in basophilic granulocytes and lung function tests were applied before and after a Monday shift and after a Friday shift. Work-related symptoms of respiratory allergy were present in 23% of all workers, but were significantly more frequent in the most exposed group in the platinum refinery (52.4%). Of all workers, 18.7% had a positive skin-prick test with platinum salt. As compared to the other workers, the workers with work-related symptoms of respiratory allergy had significantly more positive skin-prick tests (64.3%) and a higher total IgE and platinum-specific IgE; they did not, however, show higher histamine release. In the course of the week, a significant fall in lung function, namely in FEV1 and FEF25, was recorded in the group of workers with work-related symptoms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0340-0131
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-60
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1468794-Adult,
pubmed-meshheading:1468794-Cross-Sectional Studies,
pubmed-meshheading:1468794-Female,
pubmed-meshheading:1468794-Forced Expiratory Volume,
pubmed-meshheading:1468794-Germany,
pubmed-meshheading:1468794-Humans,
pubmed-meshheading:1468794-Immunoglobulin E,
pubmed-meshheading:1468794-Incidence,
pubmed-meshheading:1468794-Intradermal Tests,
pubmed-meshheading:1468794-Male,
pubmed-meshheading:1468794-Occupational Diseases,
pubmed-meshheading:1468794-Platinum,
pubmed-meshheading:1468794-Respiratory Hypersensitivity
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pubmed:year |
1992
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pubmed:articleTitle |
Prevalence of respiratory allergy in a platinum refinery.
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pubmed:affiliation |
Ministry of Women, Work and Social Welfare, Department of Occupational Safety, Wiesbaden, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article
|