rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1-2
|
pubmed:dateCreated |
2003-12-22
|
pubmed:abstractText |
The kallikrein family is a group of 15 serine protease genes clustered on chromosome 19q13.4. Human kallikrein gene 13 (KLK13) is a member of this family and encodes for a trypsin-like, secreted serine protease (hK13). Given that other kallikreins are sequestered by serum protease inhibitors, we hypothesized that hK13 may also interact with similar inhibitors. Our objective was to identify serum protease inhibitors that interact with human hK13.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0009-8981
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
339
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
157-67
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14687906-Animals,
pubmed-meshheading:14687906-Ascitic Fluid,
pubmed-meshheading:14687906-Chromatography, Gel,
pubmed-meshheading:14687906-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:14687906-Female,
pubmed-meshheading:14687906-Humans,
pubmed-meshheading:14687906-Hydrolysis,
pubmed-meshheading:14687906-Iodine Radioisotopes,
pubmed-meshheading:14687906-Kallikreins,
pubmed-meshheading:14687906-Molecular Weight,
pubmed-meshheading:14687906-Ovarian Neoplasms,
pubmed-meshheading:14687906-Protease Inhibitors,
pubmed-meshheading:14687906-Protein Binding,
pubmed-meshheading:14687906-Recombinant Proteins,
pubmed-meshheading:14687906-Semen,
pubmed-meshheading:14687906-Trypsin
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pubmed:year |
2004
|
pubmed:articleTitle |
Complex formation between human kallikrein 13 and serum protease inhibitors.
|
pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|