|
pubmed:abstractText |
Pulmonary fibrosis (PF) induced by anticancerogenic bleomycin (BLM) is one of the more common side effects encountered during cancer treatment. It has been suggested in the last decades that the main responsible agent in PF is reactive oxygen species which were generated also in normal physiological conditions in the human body. In this experimental study, we investigated the preventive or attenuating effects of caffeic acid phenethyl ester (CAPE) that has been demonstrated to have anti-inflammatory, cytocytatic, anticancerogenic, antiprolipherative and antioxidant effects on BLM-induced PF.
|
|
pubmed:affiliation |
Department of Biochemistry, Gaziosmanpasa University, Medical School, Arastirma Hastanesi, 60100 Tokat, Turkey. huseyinozyurt@hotmail.com
|
