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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1993-1-27
|
| pubmed:abstractText |
Catecholamine levels and associated cardiovascular responses were determined in 21 control and 30 term infants with meconium-stained amniotic fluid (MSAF). Cord arterial blood was obtained for determination for norepinephrine (NE) and epinephrine (EPI) levels; cardiovascular measurements included heart rate and systolic blood pressure at 30 min. Pregnancy was uncomplicated in all cases. The total length of labor 964 +/- 402 versus 555 +/- 312 min (P < 0.001) and active phase of labor 300 +/- 261 versus 135 +/- 104 min (P < 0.001) were significantly longer in MSAF infants when compared to controls. The 1 min Apgar score was < 7 (range 1-6) in 11 of 30 MSAF infants versus 0 of 21 control infants; these 11 infants required positive pressure ventilation for approximately 60 s secondary to transient respiratory depression (RD). The 5 min Apgar score was > 7 in 49 of the 51 infants. Infants with MSAF exhibited a higher PaCO2 (6.89 +/- 1.17 vs 6.24 +/- 1.17 mmHg; P < 0.02) and lower pH (7.25 +/- 0.06 vs 7.29 +/- 0.05; P < 0.02) compared to controls. Infants with transient RD demonstrated the most marked arterial blood gas differences, i.e., PCO2 7.41 +/- 1.30 mmHg (P < 0.001), pH 7.21 +/- 0.07 (P < 0.001) and base deficit -6 +/- 4 versus -3 +/- 2.8 (P < 0.001) when compared to controls. NE and EPI levels were significantly higher in MSAF versus control infants, i.e., 12600 +/- 3040 versus 3740 +/- 1000 pg/ml (SEM) (P < 0.02) and 1550 +/- 250 versus 620 +/- 130 pg/ml (P < 0.001) respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0340-6199
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
151
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
855-60
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1468463-Amniotic Fluid,
pubmed-meshheading:1468463-Carbon Dioxide,
pubmed-meshheading:1468463-Case-Control Studies,
pubmed-meshheading:1468463-Epinephrine,
pubmed-meshheading:1468463-Female,
pubmed-meshheading:1468463-Fetal Blood,
pubmed-meshheading:1468463-Heart Rate, Fetal,
pubmed-meshheading:1468463-Humans,
pubmed-meshheading:1468463-Hydrogen-Ion Concentration,
pubmed-meshheading:1468463-Infant, Newborn,
pubmed-meshheading:1468463-Labor, Obstetric,
pubmed-meshheading:1468463-Meconium,
pubmed-meshheading:1468463-Norepinephrine,
pubmed-meshheading:1468463-Oxygen,
pubmed-meshheading:1468463-Pregnancy
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Catecholamine levels and associated cardiovascular responses in infants with meconium-stained amniotic fluid.
|
| pubmed:affiliation |
Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110.
|
| pubmed:publicationType |
Journal Article
|