14684328

Source:http://linkedlifedata.com/resource/pubmed/id/14684328

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001128, umls-concept:C0002594, umls-concept:C0016904, umls-concept:C0441712, umls-concept:C1517001
pubmed:issue	1
pubmed:dateCreated	2003-12-19
pubmed:abstractText	Inactivation of pyridoxal 5'-phosphate (PLP)-dependent gamma-aminobutryic acid aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (SADFA) gives pyridoxamine 5'-phosphate, not the expected SADFA-PLP aromatization product. Inactivation appears to proceed by a Michael addition/hydrolysis mechanism instead.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/NS 15703
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/4-Aminobutyrate Transaminase, http://linkedlifedata.com/resource/pubmed/chemical/Carboxylic Acids
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0960-894X
pubmed:author	pubmed-author:FuMengmengM, pubmed-author:SilvermanRichard BRB
pubmed:issnType	Print
pubmed:day	5
pubmed:volume	14
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	203-6
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:14684328-4-Aminobutyrate Transaminase, pubmed-meshheading:14684328-Carboxylic Acids, pubmed-meshheading:14684328-Dose-Response Relationship, Drug
pubmed:year	2004
pubmed:articleTitle	Inactivation of gamma-aminobutyric acid aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid does not proceed by the expected aromatization mechanism.
pubmed:affiliation	Department of Chemistry, Northwestern University, Evanston, IL 60208-3113, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S.