| pubmed-article:14684323 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0226896 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0205531 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C1527415 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0074785 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0935763 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:14684323 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:14684323 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:14684323 | pubmed:dateCreated | 2003-12-19 | lld:pubmed |
| pubmed-article:14684323 | pubmed:abstractText | Inhibition of the sodium hydrogen exchanger isoform-1 (NHE-1) has been shown to limit damage to the myocardium under ischemic conditions in animals. While most known NHE-1 inhibitors are acylguanidines, this report describes the design and synthesis of a series of heterocyclic inhibitors of NHE-1 including aminoimidazoles with undiminished in vitro activity and oral bioavailability. | lld:pubmed |
| pubmed-article:14684323 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14684323 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14684323 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14684323 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:14684323 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:WuShung CSC | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:LiuWenW | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:ChenBang-ChiB... | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:AtwalKarnail... | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:KirbyMarkM | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:CombsDonald... | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:AhmadSaleemS | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:NguKhehyongK | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:WeinsteinDavi... | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:ChandrasenaGa... | lld:pubmed |
| pubmed-article:14684323 | pubmed:author | pubmed-author:DorsoCharles... | lld:pubmed |
| pubmed-article:14684323 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14684323 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:14684323 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:14684323 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14684323 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14684323 | pubmed:pagination | 177-80 | lld:pubmed |
| pubmed-article:14684323 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:meshHeading | pubmed-meshheading:14684323... | lld:pubmed |
| pubmed-article:14684323 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:14684323 | pubmed:articleTitle | Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1. | lld:pubmed |
| pubmed-article:14684323 | pubmed:affiliation | Bristol-Myers Squibb Pharmaceutical Research Institute, PO Box 4000, Princeton, NJ 08543, USA. saleem.ahmad@bms.com | lld:pubmed |
| pubmed-article:14684323 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14684323 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:14684323 | lld:chembl |
