rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-12-17
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pubmed:abstractText |
To evaluate the impact of dihydrofolate reductase (DHFR) and reduced folate carrier (RFC) genes on methotrexate (MTX) resistance in osteosarcoma cells in relation to retinoblastoma (RB1) gene status.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic,
http://linkedlifedata.com/resource/pubmed/chemical/Hexosyltransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Methotrexate,
http://linkedlifedata.com/resource/pubmed/chemical/O-antigen polymerase,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Reduced Folate Carrier Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Retinoblastoma Protein,
http://linkedlifedata.com/resource/pubmed/chemical/SLC19A1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrahydrofolate Dehydrogenase
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0923-7534
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pubmed:author |
pubmed-author:BeniniSS,
pubmed-author:ChanoTT,
pubmed-author:HattingerC-MCM,
pubmed-author:MandalR NRN,
pubmed-author:MauriciDD,
pubmed-author:PaselloMM,
pubmed-author:PiccoVV,
pubmed-author:Reverter-BranchatGG,
pubmed-author:ScotlandiKK,
pubmed-author:SerraMM,
pubmed-author:ShenJ-NJN
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-60
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:14679136-Antimetabolites, Antineoplastic,
pubmed-meshheading:14679136-Drug Resistance, Neoplasm,
pubmed-meshheading:14679136-Gene Amplification,
pubmed-meshheading:14679136-Gene Deletion,
pubmed-meshheading:14679136-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:14679136-Hexosyltransferases,
pubmed-meshheading:14679136-Humans,
pubmed-meshheading:14679136-Membrane Proteins,
pubmed-meshheading:14679136-Membrane Transport Proteins,
pubmed-meshheading:14679136-Methotrexate,
pubmed-meshheading:14679136-Osteosarcoma,
pubmed-meshheading:14679136-RNA, Messenger,
pubmed-meshheading:14679136-Reduced Folate Carrier Protein,
pubmed-meshheading:14679136-Retinoblastoma Protein,
pubmed-meshheading:14679136-Tetrahydrofolate Dehydrogenase,
pubmed-meshheading:14679136-Tumor Cells, Cultured
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pubmed:year |
2004
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pubmed:articleTitle |
Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells.
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pubmed:affiliation |
Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli, Bologna, Italy. massimo.serra@ior.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't
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