Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2003-12-17
pubmed:abstractText
To evaluate the impact of dihydrofolate reductase (DHFR) and reduced folate carrier (RFC) genes on methotrexate (MTX) resistance in osteosarcoma cells in relation to retinoblastoma (RB1) gene status.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic, http://linkedlifedata.com/resource/pubmed/chemical/Hexosyltransferases, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Methotrexate, http://linkedlifedata.com/resource/pubmed/chemical/O-antigen polymerase, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Reduced Folate Carrier Protein, http://linkedlifedata.com/resource/pubmed/chemical/Retinoblastoma Protein, http://linkedlifedata.com/resource/pubmed/chemical/SLC19A1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Tetrahydrofolate Dehydrogenase
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0923-7534
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
151-60
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:14679136-Antimetabolites, Antineoplastic, pubmed-meshheading:14679136-Drug Resistance, Neoplasm, pubmed-meshheading:14679136-Gene Amplification, pubmed-meshheading:14679136-Gene Deletion, pubmed-meshheading:14679136-Gene Expression Regulation, Neoplastic, pubmed-meshheading:14679136-Hexosyltransferases, pubmed-meshheading:14679136-Humans, pubmed-meshheading:14679136-Membrane Proteins, pubmed-meshheading:14679136-Membrane Transport Proteins, pubmed-meshheading:14679136-Methotrexate, pubmed-meshheading:14679136-Osteosarcoma, pubmed-meshheading:14679136-RNA, Messenger, pubmed-meshheading:14679136-Reduced Folate Carrier Protein, pubmed-meshheading:14679136-Retinoblastoma Protein, pubmed-meshheading:14679136-Tetrahydrofolate Dehydrogenase, pubmed-meshheading:14679136-Tumor Cells, Cultured
pubmed:year
2004
pubmed:articleTitle
Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells.
pubmed:affiliation
Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli, Bologna, Italy. massimo.serra@ior.it
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, Non-U.S. Gov't