Linked Life Data

14678639

Source:http://linkedlifedata.com/resource/pubmed/id/14678639

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-12-17
pubmed:abstractText
This review emphasises the particular difficulties encountered in confirming a suspected case of cutaneous or visceral leishmaniasis when that case is co-infected with HIV. HIV infection appears to have a more profound impact on the development of visceral leishmaniasis than on the evolution of the purely cutaneous disease. The various techniques available for immunological, parasitological and molecular diagnosis are presented and evaluated. The value of serodiagnosis for the detection of antileishmanial antibodies is in part dependent on the antigens used. Western blots may have a use not only in diagnosis but also in predicting the cases of HIV infection that are at most risk of developing symptomatic leishmaniasis. The presence of leishmanial parasites may still only be demonstrated incontrovertibly by the microscopical examination of smears or the culture of blood or biopsy samples. The use of cultures not only permits diagnosis but also detailed study of the parasites. The potential use of PCR in diagnosis is explored and related to other possible tests. A recommended, standardized procedure for the diagnosis of leishmaniasis in HIV-infected patients is presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0003-4983
pubmed:author
pubmed:issnType
Print
pubmed:volume
97 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
115-33
pubmed:dateRevised
2009-5-18
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
The biological diagnosis of leishmaniasis in HIV-infected patients.
pubmed:affiliation
Service de Parasitologie-Mycologie, UMR BIPAR 956, Hôpital Henri Mondor, Avenue du Général de Lattre de Tassigny, 94010 Créteil, France. deniau@univ-paris12.fr
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't