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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16 Pt 1
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pubmed:dateCreated |
2003-12-16
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pubmed:abstractText |
Induction chemotherapy with carboplatin and paclitaxel followed by concomitant TFHX (paclitaxel, infusional 5-fluorouracil, hydroxyurea, and twice-daily radiation therapy administered every other week) has resulted in 70% 3-year survival in stage IV patients. Locoregional and distant control rates were 94 and 93%, respectively. In an attempt to decrease toxicity without compromising local control, a second cohort of patients was treated with a lower dose of radiation to sites of potential microscopic disease.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:ArgirisAthanassiosA,
pubmed-author:BrocksteinBruce EBE,
pubmed-author:HarafDaniel JDJ,
pubmed-author:ListMarcy AMA,
pubmed-author:MittalBharat BBB,
pubmed-author:PelzerHaroldH,
pubmed-author:PortugalLouisL,
pubmed-author:RosenFred RFR,
pubmed-author:StensonKerstinK,
pubmed-author:VokesEverett EEE,
pubmed-author:WeichselbaumRalph RRR,
pubmed-author:WittMary EllynME
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5936-43
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14676118-Adult,
pubmed-meshheading:14676118-Aged,
pubmed-meshheading:14676118-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:14676118-Carboplatin,
pubmed-meshheading:14676118-Carcinoma, Squamous Cell,
pubmed-meshheading:14676118-Cohort Studies,
pubmed-meshheading:14676118-Combined Modality Therapy,
pubmed-meshheading:14676118-Disease Progression,
pubmed-meshheading:14676118-Disease-Free Survival,
pubmed-meshheading:14676118-Female,
pubmed-meshheading:14676118-Fluorouracil,
pubmed-meshheading:14676118-Head and Neck Neoplasms,
pubmed-meshheading:14676118-Humans,
pubmed-meshheading:14676118-Hydroxyurea,
pubmed-meshheading:14676118-Male,
pubmed-meshheading:14676118-Middle Aged,
pubmed-meshheading:14676118-Paclitaxel,
pubmed-meshheading:14676118-Quality of Life,
pubmed-meshheading:14676118-Radiotherapy Dosage,
pubmed-meshheading:14676118-Remission Induction,
pubmed-meshheading:14676118-Survival Rate
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pubmed:year |
2003
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pubmed:articleTitle |
Induction chemotherapy followed by concomitant TFHX chemoradiotherapy with reduced dose radiation in advanced head and neck cancer.
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pubmed:affiliation |
Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois 60637-1470, USA. dharaf@mcis.bsd.uchicago.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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