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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2003-12-15
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pubmed:abstractText |
The pathologic mechanisms responsible for organ-specific tissue damage in primary Sjögren's syndrome (SS) remain unclear, but it has been suggested that the pathology is mediated by autoreactive CD4+ T cells infiltrating the salivary and lacrimal glands. This study was undertaken to investigate whether alpha-fodrin autoantigen-specific autoreactive CD4+ T cells are capable of inducing autoimmune lesions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3603-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14674013-Adoptive Transfer,
pubmed-meshheading:14674013-Amino Acid Sequence,
pubmed-meshheading:14674013-Animals,
pubmed-meshheading:14674013-Base Sequence,
pubmed-meshheading:14674013-CD4-Positive T-Lymphocytes,
pubmed-meshheading:14674013-Carrier Proteins,
pubmed-meshheading:14674013-Complementarity Determining Regions,
pubmed-meshheading:14674013-Disease Models, Animal,
pubmed-meshheading:14674013-Mice,
pubmed-meshheading:14674013-Mice, Mutant Strains,
pubmed-meshheading:14674013-Microfilament Proteins,
pubmed-meshheading:14674013-Molecular Sequence Data,
pubmed-meshheading:14674013-Sjogren's Syndrome,
pubmed-meshheading:14674013-Specific Pathogen-Free Organisms
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pubmed:year |
2003
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pubmed:articleTitle |
Development of autoimmune exocrinopathy resembling Sjögren's syndrome in adoptively transferred mice with autoreactive CD4+ T cells.
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pubmed:affiliation |
Tokushima University School of Dentistry, Tokushima, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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