Source:http://linkedlifedata.com/resource/pubmed/id/14673584
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2003-12-15
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pubmed:abstractText |
POEMS/Crow-Fukase syndrome is a rare multisystem disorder associated with elevated vascular endothelial growth factor (VEGF), which clinically presents with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes. We report a case of POEMS syndrome due to a gammopathy of undetermined significance with thrombocytosis, vitamin B(12) deficiency, highly elevated VEGF and in addition to glomeruloid angiomas two previously undescribed proliferative vascular lesions: a spinal arteriovenous fistula and a plexogenic pulmonary arteriopathy, which ultimately resulted in lethal pulmonary hypertension. We assume that the high VEGF levels caused the vascular abnormalities observed in our patient.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0340-5354
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
250
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1488-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14673584-Adult,
pubmed-meshheading:14673584-Arteriovenous Fistula,
pubmed-meshheading:14673584-Female,
pubmed-meshheading:14673584-Humans,
pubmed-meshheading:14673584-Lung,
pubmed-meshheading:14673584-Lung Diseases,
pubmed-meshheading:14673584-POEMS Syndrome,
pubmed-meshheading:14673584-Paraproteinemias,
pubmed-meshheading:14673584-Spinal Cord,
pubmed-meshheading:14673584-Spinal Cord Diseases,
pubmed-meshheading:14673584-Thrombocytosis,
pubmed-meshheading:14673584-Vascular Diseases,
pubmed-meshheading:14673584-Vascular Endothelial Growth Factor A,
pubmed-meshheading:14673584-Vitamin B 12 Deficiency
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pubmed:year |
2003
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pubmed:articleTitle |
Multiple vascular abnormalities and a paradoxical combination of vitamin B12 deficiency and thrombocytosis in a case with POEMS syndrome.
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pubmed:affiliation |
Research Group Protective Signaling, Zentrum für Molekulare Neurobiologie and Department of Neurology, University Hospital Hamburg-Eppendorf, Germany. lewerenz@zmnh.uni-hamburg.de
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pubmed:publicationType |
Journal Article,
Case Reports
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