Linked Life Data

146734

Source:http://linkedlifedata.com/resource/pubmed/id/146734

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1978-4-17
pubmed:abstractText
1. Extension of a frog muscle spindle evoked a discharge of impulses in its sensory axon. The adaptation of the discharge after the dynamic phase of stretching occurred in two phases. At first the impulse train was almost regular and adapted quickly, but later this gave place to a phase of slower adaptation in which the variability of discharge was much increased. 2. The discharge of action potentials by the muscle spindle depressed the response of the receptor to a subsequent extension. This was true whether they were elicited antidromically by afferent stimulation or orthodromically by longitudinal vibration. This depression had its most marked effect on the first phase of adaptation where it greatly increased the rate of adaptation. The second, slower, phase of adaptation was little influenced. 3. The depression increased with the duration and with the frequency of afferent stimulation. It persisted for about 300 msec. 4. The results show that the properties of the spike generating mechanisms in the muscle spindle are modified by previous discharge and that this modification may influence the overall properties of the receptor. 5. The fact that afferent stimulation has different effects on the two phases of adaptation is consistent with the suggestion that the impulse train evoked by extension is derived from more than one spike generator within the muscle spindle.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-13368111, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-134147, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-14298108, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-15395191, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-16994203, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-4237617, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-4238530, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-4251857, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-4280441, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-4281835, http://linkedlifedata.com/resource/pubmed/commentcorrection/146734-4850455
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
274
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
397-408
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Modification by previous afferent discharge of the adaptation of frog muscle spindles following an extension.
pubmed:publicationType
Journal Article, In Vitro