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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2003-12-15
pubmed:abstractText
The present study was designed to evaluate whether feeding supplemental energy would improve the metabolic profile and alleviate some of the immunosuppression typically noted during the periparturient period in dairy cows with Johne's disease. Twelve dairy cows naturally infected with Mycobacterium paratuberculosis were fitted with rumen cannulas in late gestation and assigned to treatment groups: control, n = 6; or stuffed, n = 6. Cows in the control group were allowed to consume feed ad libitum. Cows assigned to the stuffed treatment group were also fed ad libitum but received additional total mixed rations by manually stuffing their rumens with refused feed to maintain dry matter intake of 2% body weight per day before calving and 2.5% body weight per day after calving. Serum nonesterified fatty acid levels were significantly decreased in stuffed cows compared with control cows, indicating that stuffing to maintain dry matter intake improved the energy balance in the cows. In addition, periparturient serum calcium and magnesium concentrations were significantly higher in stuffed cows. Stuffing modulated cell-mediated immunity by reducing lymphocyte proliferative responses to T-cell mitogens during early lactation. Stuffing resulted in an increase in the secretion of in vitro immunoglobulin by peripheral blood mononuclear cells after parturition when compared to control cows. These data demonstrate that energy balance is improved by providing additional energy in this manner and suggest energy supplementation can improve some aspects of immune function during the periparturient period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-0302
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3527-35
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:14672182-Animal Feed, pubmed-meshheading:14672182-Animal Nutritional Physiological Phenomena, pubmed-meshheading:14672182-Animals, pubmed-meshheading:14672182-Blood Glucose, pubmed-meshheading:14672182-Calcium, pubmed-meshheading:14672182-Catheterization, pubmed-meshheading:14672182-Cattle, pubmed-meshheading:14672182-Cattle Diseases, pubmed-meshheading:14672182-Energy Intake, pubmed-meshheading:14672182-Fatty Acids, Nonesterified, pubmed-meshheading:14672182-Female, pubmed-meshheading:14672182-Immunity, Cellular, pubmed-meshheading:14672182-Immunoglobulin G, pubmed-meshheading:14672182-Immunoglobulin M, pubmed-meshheading:14672182-Lymphocyte Activation, pubmed-meshheading:14672182-Magnesium, pubmed-meshheading:14672182-Neutrophils, pubmed-meshheading:14672182-Paratuberculosis, pubmed-meshheading:14672182-Parturition, pubmed-meshheading:14672182-Postpartum Period, pubmed-meshheading:14672182-Pregnancy, pubmed-meshheading:14672182-Random Allocation, pubmed-meshheading:14672182-Rumen
pubmed:year
2003
pubmed:articleTitle
Effects of supplemental energy on metabolic and immune measurements in periparturient dairy cows with Johne's disease.
pubmed:affiliation
USDA-ARS, National Animal Disease Center, Bacterial Diseases of Livestock Research Unit, Ames, IA 50010, USA. jstabel@nadc.ars.usda.gov
pubmed:publicationType
Journal Article