Linked Life Data

14668934

Source:http://linkedlifedata.com/resource/pubmed/id/14668934

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2003-12-11
pubmed:abstractText
Wound healing is a complex biological process that requires cellular interactions between a variety of cells, including fibroblasts, myofibroblasts, smooth muscle cells, endothelial cells, keratinocytes and immune cells. These interactions are mediated by numerous factors such as growth factors, hormones, blood components and second messengers. Several growth factors that are released at the wound site are presumed to be necessary for wound healing. These include epidermal growth factor (EGF), fibroblast growth factor (FGF), insulin-like growth factor (IGF), keratinocyte growth factor (KGF), platelet-derived growth factor (PDGF), transforming growth factor (TGF) and vascular endothelial growth factor (VEGF). The clinical use of growth factors to stimulate the healing of wounds is currently being investigated. Several growth factors, including PDGF, FGF-2, IGF and KGF, have been used in clinical trials, and PDGF is currently approved for use in human medicine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1699-3993
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
787-800
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Wound healing: the role of growth factors.
pubmed:affiliation
Department of Animal and Range Sciences and Cell Biology Center, North Dakota State University, Fargo, North Dakota 58105, USA. Anna.Grazul-Bilska@ndsu.nodak.edu
pubmed:publicationType
Journal Article, Review