Linked Life Data

14667379

Source:http://linkedlifedata.com/resource/pubmed/id/14667379

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-12-11
pubmed:abstractText
Evolutionary theories of senescence postulate that lifespan is determined by the age-dependent decrease in the effects of natural selection. Factors that influence survival and reproduction at early life stages have a larger impact on fitness than factors that influence later life stages. According to these views, selection for rapid sexual maturation and a steep age-dependent decrease in fitness drive the evolution of short lifespans. Here, we report on the survival trajectory of Nothobranchius furzeri (Pisces: Ciprinodontidae): a member of a group of annual species found in temporary bodies of water whose life expectancy in the wild is limited to a few months. We find that maximum survival of N. furzeri in the laboratory is less than 12 weeks. The temporal trajectory of survival shows an age-dependent increase in the mortality rate that is typical of organisms with defined lifespans. The lifespan of N. furzeri is exceptionally short for a vertebrate: owing to its small size and the possibility of propagation in captivity, N. furzeri could be used as a convenient model for ageing research.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-10716732, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-11017081, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-11792861, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-11869731, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-12213556, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-42059, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-4696516, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-5042930, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-6015424, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-7475352, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-8707063, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-9007227, http://linkedlifedata.com/resource/pubmed/commentcorrection/14667379-9599158
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0962-8452
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
270 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S189-91
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Extremely short lifespan in the annual fish Nothobranchius furzeri.
pubmed:affiliation
Associazione Italiana Killifish, Canossa 42026, Italy.
pubmed:publicationType
Journal Article, Comparative Study