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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-12-10
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pubmed:abstractText |
Polymorphisms in the Nicastrin (NCSTN) gene have recently been associated with familial early-onset Alzheimer's disease (AD). The authors genotyped four NCTSN polymorphisms in a large cohort of 489 AD cases (including 158 sporadic early-onset AD cases and 95 familial early-onset AD cases) and 386 controls but failed to replicate the association between NCSTN haplotype B and AD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0304-3940
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pubmed:author |
pubmed-author:BriceAlexisA,
pubmed-author:BrunChristopheC,
pubmed-author:CampionDominiqueD,
pubmed-author:ChansacCélineC,
pubmed-author:CousinEmmanuelleE,
pubmed-author:DeleuzeJean-FrançoisJF,
pubmed-author:DuboisBrunoB,
pubmed-author:FrebourgThierryT,
pubmed-author:GéninEmmanuelleE,
pubmed-author:HannequinDidierD,
pubmed-author:MacéSandrineS,
pubmed-author:PradierLaurentL,
pubmed-author:RicardSylvainS
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pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
353
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14664923-Age of Onset,
pubmed-meshheading:14664923-Aged,
pubmed-meshheading:14664923-Alzheimer Disease,
pubmed-meshheading:14664923-Amyloid Precursor Protein Secretases,
pubmed-meshheading:14664923-Apolipoprotein E4,
pubmed-meshheading:14664923-Apolipoproteins E,
pubmed-meshheading:14664923-France,
pubmed-meshheading:14664923-Gene Frequency,
pubmed-meshheading:14664923-Genotype,
pubmed-meshheading:14664923-Haplotypes,
pubmed-meshheading:14664923-Humans,
pubmed-meshheading:14664923-Membrane Glycoproteins,
pubmed-meshheading:14664923-Middle Aged,
pubmed-meshheading:14664923-Polymerase Chain Reaction,
pubmed-meshheading:14664923-Polymorphism, Single Nucleotide
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pubmed:year |
2003
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pubmed:articleTitle |
No replication of the association between the Nicastrin gene and familial early-onset Alzheimer's disease.
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pubmed:affiliation |
Aventis Pharma, Evry Genetics Center and Neurodegenerative disease group, Paris Research Center, 13 Quai Jules Guesde, 94400 Vitry-sur-Seine, France.
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pubmed:publicationType |
Journal Article,
Comparative Study
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