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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-12-10
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pubmed:abstractText |
Combination therapy with aspirin plus ticlopidine has become the reference antithrombotic therapy after coronary stenting. However despite its effectiveness, ticlopidine is associated with a significant incidence of severe side effects. Thus, clopidogrel, a ticlopidine analogue with an excellent safety profile, has been introduced in clinical practice. To date only a few, underpowered studies comparing the clinical efficacy of clopidogrel and aspirin versus standard combination therapy after coronary stenting have been performed and the odds ratios (OR) vary substantially among them. The purpose of the present investigation was to update the data regarding this issue by means of a formal meta-analysis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1129-471X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
677-84
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14664280-Adult,
pubmed-meshheading:14664280-Aged,
pubmed-meshheading:14664280-Combined Modality Therapy,
pubmed-meshheading:14664280-Confidence Intervals,
pubmed-meshheading:14664280-Coronary Disease,
pubmed-meshheading:14664280-Dose-Response Relationship, Drug,
pubmed-meshheading:14664280-Drug Administration Schedule,
pubmed-meshheading:14664280-Evaluation Studies as Topic,
pubmed-meshheading:14664280-Female,
pubmed-meshheading:14664280-Humans,
pubmed-meshheading:14664280-Male,
pubmed-meshheading:14664280-Middle Aged,
pubmed-meshheading:14664280-Odds Ratio,
pubmed-meshheading:14664280-Prognosis,
pubmed-meshheading:14664280-Randomized Controlled Trials as Topic,
pubmed-meshheading:14664280-Risk Assessment,
pubmed-meshheading:14664280-Stents,
pubmed-meshheading:14664280-Survival Analysis,
pubmed-meshheading:14664280-Ticlopidine,
pubmed-meshheading:14664280-Treatment Outcome,
pubmed-meshheading:14664280-Vascular Patency
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pubmed:year |
2003
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pubmed:articleTitle |
Safety and efficacy evaluation of clopidogrel compared to ticlopidine after stent implantation: an updated meta-analysis.
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pubmed:affiliation |
Cardiology Division, Maggiore Hospital, Bologna, Italy. gcas@fastmail.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Meta-Analysis
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