rdf:type |
|
lifeskim:mentions |
umls-concept:C0018270,
umls-concept:C0021469,
umls-concept:C0079189,
umls-concept:C0205263,
umls-concept:C0332283,
umls-concept:C0915737,
umls-concept:C1335872,
umls-concept:C1421249,
umls-concept:C1518440,
umls-concept:C1710082,
umls-concept:C1879547
|
pubmed:issue |
12
|
pubmed:dateCreated |
2003-12-9
|
pubmed:abstractText |
Limitin, an interferon-like cytokine, suppresses B lymphopoiesis through ligation of the interferon-alpha/beta (IFN-alpha/beta) receptor. The aim of this study was to examine the intracellular signal transduction pathways activated by limitin.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Daxx protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Intracellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Jak1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Janus Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mxra8 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/STAT1 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Stat1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/TYK2 Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/Tyk2 protein, mouse
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0301-472X
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pubmed:author |
pubmed-author:AokiKenichiK,
pubmed-author:GondoHisashiH,
pubmed-author:HaradaMineM,
pubmed-author:HaroTakashiT,
pubmed-author:IshikawaFumihikoF,
pubmed-author:KamezakiKenjirouK,
pubmed-author:MatsudaTadashiT,
pubmed-author:MiyamotoToshihiroT,
pubmed-author:MuromotoRyutaR,
pubmed-author:NagafuchiSeihoS,
pubmed-author:NagafujiKojiK,
pubmed-author:NakayamaKei-IchiK,
pubmed-author:NumataAkihikoA,
pubmed-author:OritaniKenjiK,
pubmed-author:ShimodaKazuyaK,
pubmed-author:TakaseKenK,
pubmed-author:TamiyaSadafumiS,
pubmed-author:YamamotoTetsuyaT,
pubmed-author:YumiokaTaroT
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pubmed:issnType |
Print
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pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1317-22
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14662340-Active Transport, Cell Nucleus,
pubmed-meshheading:14662340-Animals,
pubmed-meshheading:14662340-B-Lymphocytes,
pubmed-meshheading:14662340-Bone Marrow Cells,
pubmed-meshheading:14662340-Carrier Proteins,
pubmed-meshheading:14662340-Cell Division,
pubmed-meshheading:14662340-Cells, Cultured,
pubmed-meshheading:14662340-DNA-Binding Proteins,
pubmed-meshheading:14662340-Immunoglobulins,
pubmed-meshheading:14662340-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:14662340-Janus Kinase 1,
pubmed-meshheading:14662340-Membrane Proteins,
pubmed-meshheading:14662340-Mice,
pubmed-meshheading:14662340-Mice, Knockout,
pubmed-meshheading:14662340-Nuclear Proteins,
pubmed-meshheading:14662340-Phosphorylation,
pubmed-meshheading:14662340-Protein-Tyrosine Kinases,
pubmed-meshheading:14662340-Proteins,
pubmed-meshheading:14662340-STAT1 Transcription Factor,
pubmed-meshheading:14662340-Signal Transduction,
pubmed-meshheading:14662340-TYK2 Kinase,
pubmed-meshheading:14662340-Trans-Activators,
pubmed-meshheading:14662340-Up-Regulation
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pubmed:year |
2003
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pubmed:articleTitle |
Limitin, an interferon-like cytokine, transduces inhibitory signals on B-cell growth through activation of Tyk2, but not Stat1, followed by induction and nuclear translocation of Daxx.
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pubmed:affiliation |
The First Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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