|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013227,
umls-concept:C0014018,
umls-concept:C0051473,
umls-concept:C0071599,
umls-concept:C0144576,
umls-concept:C0456603,
umls-concept:C0606070,
umls-concept:C0868939,
umls-concept:C1280500,
umls-concept:C1450054,
umls-concept:C1708715,
umls-concept:C2346689
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|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2003-12-9
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|
pubmed:abstractText |
We successfully manufactured nanoparticles of biodegradable polymers for controlled release of paclitaxel. TPGS (d-alpha-tocopheryl polyethylene glycol 1000 succinate) could be a novel material to make nanoparticles of high drug encapsulation efficiency (EE) and desired physicochemical and pharmaceutical properties of the drug loaded nanoparticles. Among various controlling parameters in the process, the present work is to elucidate the effects of the surfactant stabilizer and the drug loading ratio.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
Nov
|
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pubmed:issn |
0724-8741
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
20
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1864-72
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
|
|
pubmed:year |
2003
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|
pubmed:articleTitle |
PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio.
|
|
pubmed:affiliation |
Division of Bioengineering, The National University of Singapore, 9 Engineering Drive 1, Singapore 117576.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
