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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-12-8
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pubmed:abstractText |
It has been reported that serotonin (5-HT) is involved in the development of pulmonary arterial hypertension (PAH) with pulmonary vascular remodeling. The purpose of the present study was to examine the role of a 5-HT2A receptor antagonist, sarpogrelate hydrochroride, in preventing or reversing monocrotaline (MCT)-induced PAH in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
692-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:14659815-Animals,
pubmed-meshheading:14659815-Endothelium, Vascular,
pubmed-meshheading:14659815-Hypertension, Pulmonary,
pubmed-meshheading:14659815-Lung,
pubmed-meshheading:14659815-Male,
pubmed-meshheading:14659815-Monocrotaline,
pubmed-meshheading:14659815-Nitric Oxide Synthase,
pubmed-meshheading:14659815-Nitric Oxide Synthase Type III,
pubmed-meshheading:14659815-P-Selectin,
pubmed-meshheading:14659815-Rats,
pubmed-meshheading:14659815-Rats, Sprague-Dawley,
pubmed-meshheading:14659815-Serotonin 5-HT2 Receptor Antagonists,
pubmed-meshheading:14659815-Serotonin Antagonists,
pubmed-meshheading:14659815-Succinates,
pubmed-meshheading:14659815-Survival Rate
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pubmed:year |
2003
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pubmed:articleTitle |
Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats.
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pubmed:affiliation |
Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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