Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2003-12-8
pubmed:abstractText
Primary carcinoma of the fallopian tube is a very unusual gynecologic malignancy that accounts for less than 1% of all malignancies of the female genitalia. A 55-year-old, gravida 7, para 3 woman presented with no gynecologic complaints other than backache. TVS demonstrated a 35 x 25 mm heterogeneous mass that was not clearly separated from the left ovary, and another 31 x 14 mm cystic septated lesion in the left ovary region. Pelvic MRI demonstrated a 35 x 35 x 20 mm left adnexal mass that enhanced with contrast and a neighboring tubular-cystic mass. Upper and lower gastrointestinal endoscopy revealed no malignancy. Serum CA 125-level was merkedly elevated at 369 U/ml (normal < 35 U/ml). Laparotomy revealed left hydrosalpinx and a papillary-fimbrial mass. Pelvic lymph node metastases were observed. Frozen-section analysis identified the mass as a serous adenocarcinoma. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, appendectomy, omentectomy, pelvic and para-aortic lymph node dissection, and peritoneal washing were performed. The definitive histopathological diagnosis was primary serous adenocarcinoma of the fallopian tube with six of 25 lymph node biopsies showing metastasis. Six cycles of paclitaxel (175 mg/m2) plus cisplatin (75 mg/m2) combinatin chemotherapy were administered with 3-week intervals between cycles. Second-look laparotomy was performed; there was no evidence of disease. At the time of writing 12 months after the second-look laparotomy, she was still disease-free.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0392-2936
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
557-60
pubmed:dateRevised
2006-4-24
pubmed:meshHeading
pubmed-meshheading:14658603-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:14658603-Aorta, Thoracic, pubmed-meshheading:14658603-Appendectomy, pubmed-meshheading:14658603-Cisplatin, pubmed-meshheading:14658603-Cystadenocarcinoma, Serous, pubmed-meshheading:14658603-Diagnosis, Differential, pubmed-meshheading:14658603-Fallopian Tube Neoplasms, pubmed-meshheading:14658603-Fallopian Tubes, pubmed-meshheading:14658603-Female, pubmed-meshheading:14658603-Humans, pubmed-meshheading:14658603-Hysterectomy, pubmed-meshheading:14658603-Lymph Nodes, pubmed-meshheading:14658603-Lymphatic Metastasis, pubmed-meshheading:14658603-Middle Aged, pubmed-meshheading:14658603-Neoplasm Staging, pubmed-meshheading:14658603-Omentum, pubmed-meshheading:14658603-Ovariectomy, pubmed-meshheading:14658603-Paclitaxel, pubmed-meshheading:14658603-Pelvic Neoplasms, pubmed-meshheading:14658603-Second-Look Surgery
pubmed:year
2003
pubmed:articleTitle
Management of advanced-stage primary carcinoma of the fallopian tube: case report and literature review.
pubmed:affiliation
Department of Obstetrics and Gynecology, Baskent University, Faculty of Medicine, Ankara, Turkey.
pubmed:publicationType
Journal Article, Review, Case Reports