Linked Life Data

14656346

Source:http://linkedlifedata.com/resource/pubmed/id/14656346

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2003-12-5
pubmed:abstractText
The mechanisms behind the development of severe asthma are poorly understood. However, these patients disproportionately consume healthcare resources related to asthma. Severe asthma may develop over time, or may develop shortly after onset of the disease. The genetic and environmental elements that may be most important in the development of severe disease are poorly understood. Physiologically, these patients often have air trapping and airway collapsibility. The pathology demonstrates a heterogeneity of findings, including continued eosinophilic inflammation, an apparently different pathology, structural changes likely to be remodelling related, and predominant distal disease. Treatment remains problematic and likely will remain so until a better understanding of this disease develops.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0954-7894
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1622-8
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Mechanisms of severe asthma.
pubmed:affiliation
National Jewish Medical and Research Center, Denver, CO 80206, USA. wenzels@njc.org
pubmed:publicationType
Journal Article, Review