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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2003-12-5
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pubmed:abstractText |
Hypoxia is associated with adverse outcome for a number of solid tumors, including cervical carcinomas. Direct pO(2) measurement requires specialized equipment and expertise that is not generally available. Immunohistochemical measurement of intrinsic tissue markers of hypoxia is an alternative approach. Recent studies suggest that carbonic anhydrase IX (CA IX), which is regulated via hypoxia-inducible factor 1, is a useful intrinsic marker of tumor hypoxia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5666-74
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14654550-Adult,
pubmed-meshheading:14654550-Aged,
pubmed-meshheading:14654550-Antigens, Neoplasm,
pubmed-meshheading:14654550-Carbonic Anhydrases,
pubmed-meshheading:14654550-Carcinoma,
pubmed-meshheading:14654550-Cell Hypoxia,
pubmed-meshheading:14654550-Female,
pubmed-meshheading:14654550-Humans,
pubmed-meshheading:14654550-Lymphatic Metastasis,
pubmed-meshheading:14654550-Middle Aged,
pubmed-meshheading:14654550-Prognosis,
pubmed-meshheading:14654550-Survival Analysis,
pubmed-meshheading:14654550-Time Factors,
pubmed-meshheading:14654550-Treatment Failure,
pubmed-meshheading:14654550-Treatment Outcome,
pubmed-meshheading:14654550-Tumor Markers, Biological,
pubmed-meshheading:14654550-Uterine Cervical Neoplasms
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pubmed:year |
2003
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pubmed:articleTitle |
Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas.
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pubmed:affiliation |
Division of Experimental Therapeutics and Department of Radiation Oncology, Ontario Cancer Institute/Princess Margaret Hospital, Toronto, Ontario, Canada. david.hedley@ubn.on.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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