Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-12-4
pubmed:abstractText
In vitro block preparations of the central nervous system (CNS) are particularly valuable for study of central neuronal mechanisms controlling the respiratory and locomotor rhythms. No comparable in vitro preparation has been described previously, however, for analysis of analogous feeding rhythms. In this chapter, we present such a model. It is comprised of an in vitro brainstem-spinal cord preparation isolated from the newborn rat and mouse. Bath application to this preparation of N-methyl-D-aspartate (NMDA) induces rhythmical burst activity in the V, VII and XII nerves, which, collectively, is indicative of feeding behavior. Selected transections of the brainstem reveal that the central sucking rhythm generators for such V, VII and XII activity are separate from one another, and located segmentally in the brainstem at the level of their respective motor nuclei. We believe that use of this in vitro preparation will advance understanding of the central neuronal mechanisms controlling sucking and mastication, and the developmental transition from sucking to mastication.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0079-6123
pubmed:author
pubmed:issnType
Print
pubmed:volume
143
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-103
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Rhythm generation for food-ingestive movements.
pubmed:affiliation
Department of Physiology, Faculty of Dentistry, Tokyo Medical and Dental University, Tokyo 113-8549, Japan. yoshio-n@sk9.so-net.ne.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't