14651727

Source:http://linkedlifedata.com/resource/pubmed/id/14651727

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006949, umls-concept:C0021469, umls-concept:C0025519, umls-concept:C0075262, umls-concept:C0086418, umls-concept:C0286738, umls-concept:C1280500
pubmed:issue	5
pubmed:dateCreated	2003-12-3
pubmed:abstractText	To characterize the in vitro and in vivo inhibitory effect of stiripentol, a new anticonvulsant, on the metabolism of carbamazepine and saquinavir, which are substrates of CYP3A4.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-10565591, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-10950845, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-11162779, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-11719727, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-224884, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-2881749, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-3694494, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-671222, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-8010982, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-8801058, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-8858278, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9029057, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9252059, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9390105, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9443844, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9585800, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9765359, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9812178, http://linkedlifedata.com/resource/pubmed/commentcorrection/14651727-9929510
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7503323
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anticonvulsants, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Carbamazepine, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Dioxolanes, http://linkedlifedata.com/resource/pubmed/chemical/HIV Protease Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Saquinavir, http://linkedlifedata.com/resource/pubmed/chemical/carbamazepine epoxide, http://linkedlifedata.com/resource/pubmed/chemical/stiripentol
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0306-5251
pubmed:author	pubmed-author:CazaliNN, pubmed-author:PonsGG, pubmed-author:SHOYY, pubmed-author:TranAA, pubmed-author:TreluyerJ MJM, pubmed-author:VincentJJ, pubmed-author:d'AthisPP
pubmed:issnType	Print
pubmed:volume	56
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	526-36
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:14651727-Adolescent, pubmed-meshheading:14651727-Anticonvulsants, pubmed-meshheading:14651727-Carbamazepine, pubmed-meshheading:14651727-Child, pubmed-meshheading:14651727-Chromatography, High Pressure Liquid, pubmed-meshheading:14651727-Cytochrome P-450 CYP3A, pubmed-meshheading:14651727-Cytochrome P-450 Enzyme System, pubmed-meshheading:14651727-Dioxolanes, pubmed-meshheading:14651727-Drug Interactions, pubmed-meshheading:14651727-HIV Protease Inhibitors, pubmed-meshheading:14651727-Humans, pubmed-meshheading:14651727-Microsomes, Liver, pubmed-meshheading:14651727-Saquinavir, pubmed-meshheading:14651727-Time Factors
pubmed:year	2003
pubmed:articleTitle	Inhibitory effect of stiripentol on carbamazepine and saquinavir metabolism in human.
pubmed:affiliation	Pharmacologie, Université René Descartes, Hôpital Saint-Vincent de Paul, Assistance Publique-Hôpitaux de Paris, Paris, France.
pubmed:publicationType	Journal Article, In Vitro, Research Support, Non-U.S. Gov't