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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-5
|
pubmed:dateCreated |
1993-1-21
|
pubmed:abstractText |
Insulin-like growth factors (IGFs) I and II are proinsulin-like peptides. IGF I is produced in adult and embryonic kidney. It is likely that IGF I produced locally in adult kidney regulates processes of renal transport, metabolism and growth. Renal IGF I production is stimulated by growth hormone (GH) and by epidermal growth factor (EGF). The identity of additional factors that regulate IGF I gene expression in settings such as compensatory hypertrophy and diabetes mellitus is unknown. IGF I and IGF II produced in embryonic kidney promote the metanephrogenic process. The identity of factors that regulate metanephric IGF gene expression is yet to be determined.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0378-0392
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
253-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1465070-Autoradiography,
pubmed-meshheading:1465070-Female,
pubmed-meshheading:1465070-Humans,
pubmed-meshheading:1465070-Iodine Radioisotopes,
pubmed-meshheading:1465070-Kidney,
pubmed-meshheading:1465070-Kinetics,
pubmed-meshheading:1465070-Male,
pubmed-meshheading:1465070-Middle Aged,
pubmed-meshheading:1465070-Radioligand Assay,
pubmed-meshheading:1465070-Receptor, IGF Type 1
|
pubmed:year |
1992
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pubmed:articleTitle |
Expression of insulin-like growth factor in adult and embryonic kidney.
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pubmed:affiliation |
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Mo. 63110.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|