|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2003-12-1
|
|
pubmed:abstractText |
The region from 1.4 to 2.7 kb upstream of Drosophila melanogaster gene Sgs-3 is responsible for a 10-fold increase in Sgs-3 transcript levels in the third instar larval salivary gland. This region includes the related Sgs-7 gene from the 68C glue gene cluster as well as 400 bp of its 5' sequences. We show that two elements are involved, each contributing a modest 3-fold effect. One of these includes Sgs-7 transcribed sequences some 2.3 kb upstream of Sgs-3, although Sgs-7 transcription is not involved. Although important for the overall levels of Sgs-3 expression, they are clearly not strong, viral-like enhancer elements. We propose that many position effects observed in P element transformation studies are the consequence of insertion in the vicinity of similar elements dispersed throughout the genome and having modest effects on transcript levels.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-16453749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-2420996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-2423251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-2430796,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-2431935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-2942397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-2981637,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3006995,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3006996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3007005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3025590,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3028780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3085955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3086088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3095924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3099170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3104771,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-3935327,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-414841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6088058,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6091191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6214314,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6279311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6289436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6309411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6321149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14650430-6411930
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0261-4189
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
6
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3079-84
|
|
pubmed:dateRevised |
2010-9-21
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1987
|
|
pubmed:articleTitle |
Sps-3 transcript levels are determined by multiple remote sequence elements.
|
|
pubmed:affiliation |
Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, Unité 184 de Biologie Moléculaire et de Génie Génétique de l'INSERM, Faculté de Médecine, 11, rue Humann, 67085 Strasbourg Cédex, France.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
