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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-3-10
pubmed:abstractText
Neuroimaging studies suggest that the primary hand motor area and the cerebellum play a pivotal role in the control of finger tapping, but their differential contribution in this task is unknown. We used therefore repetitive transcranial magnetic stimulation (rTMS) in its virtual lesion mode (1 Hz, 10 min, 90% of motor threshold) to study the effects of transient disruption of the right lateral cerebellum (CB), the left primary hand motor area (M1), and the right brachial plexus (PL, control site) on various finger tapping tasks (paced finger tapping task: PFT; tapping with maximum speed: TAPMAX, and tapping with convenient speed: TAPCON) in healthy right-handed subjects. RTMS of the left M1 slowed finger tapping speed of the right hand in the TAPMAX task. This effect eliminated the right hand superiority in the TAPMAX task. In addition, rTMS of the left M1 resulted in slower tapping speeds for both hands during TAPCON. There were no other effects of rTMS on tapping speed or tapping variability. Findings indicate that M1 is essential for generating fastest finger movements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0014-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
155
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
196-203
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Slowing fastest finger movements of the dominant hand with low-frequency rTMS of the hand area of the primary motor cortex.
pubmed:affiliation
Department of Neuropsychology, Institute of Psychology, University of Zürich, Treichlerstr 10, 8032 Zürich, Switzerland. l.jaencke@psychologie.unizh.ch
pubmed:publicationType
Journal Article