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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2003-12-3
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pubmed:abstractText |
Myocardial infarction (MI) is a complex multifactorial and polygenic disorder that is thought to result from interaction between genetic make-up and various environmental factors. We previously identified a missense mutation, methionine (ATG) to isoleucine (ATC) at nucleotide 1023 (M341I), in exon 3 of the human natriuretic peptide receptor A type (hNPRA) gene. This mutation is associated with increased risk for essential hypertension (EH). The purpose of this study was to investigate association between MI and the M341I mutation in the hNPRA gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1234-1010
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
CR505-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14646971-Aged,
pubmed-meshheading:14646971-Alleles,
pubmed-meshheading:14646971-Base Sequence,
pubmed-meshheading:14646971-Case-Control Studies,
pubmed-meshheading:14646971-DNA Primers,
pubmed-meshheading:14646971-Exons,
pubmed-meshheading:14646971-Female,
pubmed-meshheading:14646971-Gene Frequency,
pubmed-meshheading:14646971-Genetic Markers,
pubmed-meshheading:14646971-Guanylate Cyclase,
pubmed-meshheading:14646971-Humans,
pubmed-meshheading:14646971-Japan,
pubmed-meshheading:14646971-Male,
pubmed-meshheading:14646971-Middle Aged,
pubmed-meshheading:14646971-Mutation, Missense,
pubmed-meshheading:14646971-Myocardial Infarction,
pubmed-meshheading:14646971-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:14646971-Receptors, Atrial Natriuretic Factor,
pubmed-meshheading:14646971-Risk Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Missense mutation of exon 3 in the type A human natriuretic peptide receptor gene is associated with myocardial infarction.
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pubmed:affiliation |
2nd Department of Internal Medicine, Nihon Medical University, Itabashi-ku, Tokyo, Japan. tnakayama@med.nihon-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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