Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-12-3
pubmed:abstractText
The spinal cord arises from the most caudal domain of the neural tube whereas the vertebrae develop from the para-axial mesoderm (namely the somites). The development of the spinal cord and the vertebrae is so intimately linked that it is more convenient to present it in the same chapter. The neural tube is formed from the neural plate during neurulation. This tube is submitted to a double gradient of diffusible molecules that lead to the ventro-dorsal polarization of the tube. This polarization is figured as the emergence of sub-domains that contain progenitors engaged in a specific lineage. Axial organs induce the dissociation of the somites, giving rise to the dermatome, myotome and sclerotome. Vertebrae derive from the sclerotome after the so-called resegmentation of the somites. During this process, a caudal hemi-somite is associated with the rostral hemi-somite of the next caudal somite to differentiate into the vertebra. The occipital bone forms the major part of the walls of the posterior fossa. This bone develops from the para-axial mesoderm for its sub-tentorial part whereas its sus-tentorial derives from neural crest cells.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0028-3770
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
503-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Neurosurgical embryology. Part 7: Development of the spinal cord, the spine and the posterior fossa].
pubmed:affiliation
Laboratoire d'Histologie et Embryologie et UMR CNRS 7000, Faculté de Médecine Pitié-Salpêtrière-Université Paris 6.
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't