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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
2003-12-3
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pubmed:abstractText |
To determine the frequency of mismatch repair (MMR) gene germline mutations in endometrial cancer patients who were diagnosed at less than 50 years of age; to relate the presence of mutations to family history, histopathologic data, presence of tumor microsatellite instability (MSI), and immunostaining; and to formulate criteria for genetic testing in these patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/G-T mismatch-binding protein,
http://linkedlifedata.com/resource/pubmed/chemical/MLH1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MSH2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MutS Homolog 2 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:ArtsNeeltje J WNJ,
pubmed-author:BerendsMaran J WMJ,
pubmed-author:BuysCharles H C MCH,
pubmed-author:EkWietske BoersmavanWB,
pubmed-author:HofstraRobert M WRM,
pubmed-author:HollemaHarryH,
pubmed-author:KleibeukerJan HJH,
pubmed-author:LigtenbergMarjolijn J LMJ,
pubmed-author:MouritsMarian J EMJ,
pubmed-author:SijmonsRolf HRH,
pubmed-author:WuYingY,
pubmed-author:de VriesElisabeth G EEG,
pubmed-author:ten HoorKlaske AKA,
pubmed-author:van der SluisTinekeT,
pubmed-author:van der ZeeAte G JAG
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4364-70
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14645426-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:14645426-Adult,
pubmed-meshheading:14645426-Age of Onset,
pubmed-meshheading:14645426-Base Pair Mismatch,
pubmed-meshheading:14645426-Carcinoma, Papillary,
pubmed-meshheading:14645426-Carrier Proteins,
pubmed-meshheading:14645426-Colorectal Neoplasms, Hereditary Nonpolyposis,
pubmed-meshheading:14645426-Cystadenocarcinoma, Serous,
pubmed-meshheading:14645426-DNA, Neoplasm,
pubmed-meshheading:14645426-DNA Mutational Analysis,
pubmed-meshheading:14645426-DNA Repair,
pubmed-meshheading:14645426-DNA-Binding Proteins,
pubmed-meshheading:14645426-Endometrial Neoplasms,
pubmed-meshheading:14645426-Female,
pubmed-meshheading:14645426-Genetic Predisposition to Disease,
pubmed-meshheading:14645426-Germ-Line Mutation,
pubmed-meshheading:14645426-Humans,
pubmed-meshheading:14645426-Immunoenzyme Techniques,
pubmed-meshheading:14645426-Male,
pubmed-meshheading:14645426-Microsatellite Repeats,
pubmed-meshheading:14645426-Middle Aged,
pubmed-meshheading:14645426-MutS Homolog 2 Protein,
pubmed-meshheading:14645426-Neoplasm Proteins,
pubmed-meshheading:14645426-Nuclear Proteins,
pubmed-meshheading:14645426-Patient Selection,
pubmed-meshheading:14645426-Proto-Oncogene Proteins
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pubmed:year |
2003
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pubmed:articleTitle |
Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis.
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pubmed:affiliation |
Department of Gynaecology, University Hospital Groningen, Hanzeplein 1, PO Box 30.001, 9700 RB Groningen, The Netherlands. A.G.J.van.der.Zee@og.azg.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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