| pubmed-article:14643345 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C0369335 | lld:lifeskim |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C0012504 | lld:lifeskim |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C1328949 | lld:lifeskim |
| pubmed-article:14643345 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:14643345 | pubmed:issue | 24 | lld:pubmed |
| pubmed-article:14643345 | pubmed:dateCreated | 2003-12-3 | lld:pubmed |
| pubmed-article:14643345 | pubmed:abstractText | A series of optically pure 1,3-dioxolane nucleoside mimics was synthesized by a synthetic route that allowed incorporation of a 5R-methyl substituent from commercially available starting materials. The pyrrolo[2,3-d]pyrimidine heterocycle was chosen as a substitute for the purine derivative. Coupling of the pyrrolo[2,3-d]pyrimidine and the dioxolane was performed under solid-liquid phase transfer conditions. The ability to inhibit HCV RNA replication was assessed in a cell based subgenomic replicon assay. None of the described compounds displayed significant anti-HCV activity. | lld:pubmed |
| pubmed-article:14643345 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14643345 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14643345 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14643345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14643345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14643345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14643345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14643345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14643345 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14643345 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:14643345 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:MacCossMalcol... | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:OlsenDavid... | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:EldrupAnne... | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:TomassiniJoan... | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:CarrollSteven... | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:BhatBalkrishe... | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:BeraSanjibS | lld:pubmed |
| pubmed-article:14643345 | pubmed:author | pubmed-author:MalikLeilaL | lld:pubmed |
| pubmed-article:14643345 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14643345 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:14643345 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:14643345 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14643345 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14643345 | pubmed:pagination | 4455-8 | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:meshHeading | pubmed-meshheading:14643345... | lld:pubmed |
| pubmed-article:14643345 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14643345 | pubmed:articleTitle | Synthesis and evaluation of optically pure dioxolanes as inhibitors of hepatitis C virus RNA replication. | lld:pubmed |
| pubmed-article:14643345 | pubmed:affiliation | Department of Medicinal Chemistry, Isis Pharmaceuticals, Carlsbad, CA 92008, USA. | lld:pubmed |
| pubmed-article:14643345 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:14643345 | lld:chembl |
