|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2-3
|
|
pubmed:dateCreated |
2003-12-3
|
|
pubmed:abstractText |
The Leucine-rich Glioma Inactivated-1 (LGI1) gene is supposed to be a tumor suppressor gene involved in glial tumors. Mutations in this gene were recently found to cause autosomal dominant lateral temporal lobe epilepsy (ADLTE). We have now analysed the comorbidity in a large Norwegian ADLTE family. No evidence was found that LGI1 is a high-penetrance tumor suppressor gene associated with a serious risk for malignancies in ADLTE families.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0920-1211
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
56
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
205-8
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:14643004-Adult,
pubmed-meshheading:14643004-Aged,
pubmed-meshheading:14643004-Aged, 80 and over,
pubmed-meshheading:14643004-Epilepsy, Temporal Lobe,
pubmed-meshheading:14643004-Family,
pubmed-meshheading:14643004-Female,
pubmed-meshheading:14643004-Humans,
pubmed-meshheading:14643004-Male,
pubmed-meshheading:14643004-Middle Aged,
pubmed-meshheading:14643004-Mutation,
pubmed-meshheading:14643004-Neoplasms,
pubmed-meshheading:14643004-Proteins,
pubmed-meshheading:14643004-Risk Assessment
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
No evidence for a seriously increased malignancy risk in LGI1-caused epilepsy.
|
|
pubmed:affiliation |
Department of Neurology, St. Olavs's Hospital, Trondheim, Norway.
|
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|
