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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2003-11-25
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pubmed:abstractText |
Genetic polymorphism of interleukin (IL)-1beta is associated with differences in gastric acid suppression in response to Helicobacter pylori (H. pylori) infection. Thus, the polymorphism might affect H. pylori eradication therapy, as antibiotics used in treatment regimens may be acid sensitive. In this study, we examined the impact of IL-1beta genetic polymorphism on the cure rate of triple therapy for H. pylori in relation to cytochrome P (CYP) 2C19 genotype and antibiotic resistance.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2-Pyridinylmethylsulfinylbenzimidazo...,
http://linkedlifedata.com/resource/pubmed/chemical/Amoxicillin,
http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases,
http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/CYP2C19 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Clarithromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases,
http://linkedlifedata.com/resource/pubmed/chemical/Omeprazole,
http://linkedlifedata.com/resource/pubmed/chemical/Proton Pumps,
http://linkedlifedata.com/resource/pubmed/chemical/lansoprazole,
http://linkedlifedata.com/resource/pubmed/chemical/rabeprazole
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0002-9270
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pubmed:author |
pubmed-author:InabaTomokiT,
pubmed-author:IshikiKuniharuK,
pubmed-author:MizunoMotowoM,
pubmed-author:NagaharaYasuhiroY,
pubmed-author:OgumaKeijiK,
pubmed-author:OkadaHiroyukiH,
pubmed-author:ShiratoriYasushiY,
pubmed-author:TakeSusumuS,
pubmed-author:YamamotoKazuhideK,
pubmed-author:YokotaKenjiK,
pubmed-author:YoshidaTomowoT
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pubmed:issnType |
Print
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pubmed:volume |
98
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2403-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14638340-2-Pyridinylmethylsulfinylbenzimidazoles,
pubmed-meshheading:14638340-Adolescent,
pubmed-meshheading:14638340-Adult,
pubmed-meshheading:14638340-Amoxicillin,
pubmed-meshheading:14638340-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:14638340-Benzimidazoles,
pubmed-meshheading:14638340-Clarithromycin,
pubmed-meshheading:14638340-Drug Therapy, Combination,
pubmed-meshheading:14638340-Female,
pubmed-meshheading:14638340-Follow-Up Studies,
pubmed-meshheading:14638340-Genotype,
pubmed-meshheading:14638340-Helicobacter Infections,
pubmed-meshheading:14638340-Helicobacter pylori,
pubmed-meshheading:14638340-Humans,
pubmed-meshheading:14638340-Interleukin-1,
pubmed-meshheading:14638340-Logistic Models,
pubmed-meshheading:14638340-Male,
pubmed-meshheading:14638340-Middle Aged,
pubmed-meshheading:14638340-Mixed Function Oxygenases,
pubmed-meshheading:14638340-Multivariate Analysis,
pubmed-meshheading:14638340-Omeprazole,
pubmed-meshheading:14638340-Polymorphism, Genetic,
pubmed-meshheading:14638340-Probability,
pubmed-meshheading:14638340-Proton Pumps,
pubmed-meshheading:14638340-Statistics, Nonparametric,
pubmed-meshheading:14638340-Treatment Outcome
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pubmed:year |
2003
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pubmed:articleTitle |
Interleukin-1beta genetic polymorphism influences the effect of cytochrome P 2C19 genotype on the cure rate of 1-week triple therapy for Helicobacter pylori infection.
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pubmed:affiliation |
Department of Medicine and Medical Science, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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