Linked Life Data

14628241

Source:http://linkedlifedata.com/resource/pubmed/id/14628241

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-11-20
pubmed:abstractText
Preoperative functional neuroimaging techniques represent an appealing method to localize language areas in tumor surgery, but their reliability still needs to be confirmed by accurate comparison with more invasive but validated mapping techniques like intraoperative electrical cortical stimulation. Two patients harboring a glioma involving speech areas underwent mapping of language function by preoperative functional magnetic resonance imaging (fMRI), whose results were integrated into the neuronavigation device, and by intraoperative electrical stimulation mapping (ESM). The utilization of neuronavigation allowed us to estimate the degree of spatial correspondence between language areas detected by the two techniques. Language areas identified by functional magnetic resonance imaging on the cerebral cortex exposed during surgery corresponded to those identified by invasive mapping in both patients. It was possible to achieve a gross total tumor removal while respecting language areas in both cases, with no permanent postoperative phasic aggravation. The concordance of results between pre- and intraoperative mapping techniques in our patients indicates that preoperative fMRI language mapping may prove useful when planning the resection of intracerebral lesions in language areas. However, accurate neurofunctional imaging protocols and image analysis are crucial to obtain a preoperative language mapping that is in agreement with ESM findings.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0946-7211
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
265-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Technical refinements for validating functional MRI-based neuronavigation data by electrical stimulation during cortical language mapping.
pubmed:affiliation
Service de Neurochirurgie B, Hôpital Neurologique, BP Lyon-Monchat, 59 Boulevard Pinel, BP Lyon-Monchat, 69394 Lyon Cedex 03, France. fsignorelli@medscape.com
pubmed:publicationType
Journal Article, Case Reports