rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-11-19
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pubmed:abstractText |
GABARAP and gec1/GABARAPL1 genes encode very similar proteins belonging to a new microtubule-associated protein (MAP) family. These proteins could participate in a complex clustering, targeting and/or degrading the GABA(A) receptors on post-synaptic membrane of neurons. Using specific cDNA probes, we investigated the differential expression of both genes in 76 human tissues. Against all odds, gec1/GABARAPL1 was more expressed than GABARAP in the central nervous system (CNS), while GABARAP was more expressed in endocrine glands.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/GABARAP protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/GABARAPL1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Microtubule-Associated Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, GABA-A
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0169-328X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
26
|
pubmed:volume |
119
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
216-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14625090-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:14625090-Cell Membrane,
pubmed-meshheading:14625090-Central Nervous System,
pubmed-meshheading:14625090-Chromosomes, Human, Pair 12,
pubmed-meshheading:14625090-Chromosomes, Human, Pair 17,
pubmed-meshheading:14625090-Endocrine Glands,
pubmed-meshheading:14625090-Fetus,
pubmed-meshheading:14625090-Gene Expression,
pubmed-meshheading:14625090-Humans,
pubmed-meshheading:14625090-Microtubule-Associated Proteins,
pubmed-meshheading:14625090-Neoplasms,
pubmed-meshheading:14625090-Neurons,
pubmed-meshheading:14625090-RNA, Messenger,
pubmed-meshheading:14625090-Receptor Aggregation,
pubmed-meshheading:14625090-Receptors, GABA-A,
pubmed-meshheading:14625090-Synaptic Transmission
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pubmed:year |
2003
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pubmed:articleTitle |
Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system.
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pubmed:affiliation |
Laboratoire de Biochimie-Biologie Moléculaire, Université de Franche-Comté, U.F.R. Sciences et Techniques, 16 route de Gray, 25030 Besançon cedex, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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