Source:http://linkedlifedata.com/resource/pubmed/id/14624108
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2003-11-18
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pubmed:abstractText |
Genotypic assays are widely used tools for determining HIV-1 drug resistance and for guiding treatment. Several systems have been developed to interpret the complex influence of amino acid substitutions in HIV reverse transcriptase or protease on the phenotypic susceptibility or clinical response to the 18 available antiretroviral agents. In this review we analyse both studies comparing interpretations by different systems and studies showing correlation of interpretations with clinical outcome, in order to identify discordance and how this may affect prediction of subsequent therapy outcomes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0951-7375
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
573-80
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading | |
pubmed:year |
2003
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pubmed:articleTitle |
Impact of different HIV resistance interpretation by distinct systems on clinical utility of resistance testing.
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pubmed:affiliation |
Institute of Clinical Infectious Diseases, Catholic University of Sacred Heart, Tor Vergata University, Rome, Italy. andrea.deluca@rm.unicatt.it
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pubmed:publicationType |
Journal Article,
Review
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