Source:http://linkedlifedata.com/resource/pubmed/id/14621907
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2003-11-18
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pubmed:abstractText |
Donor-specific anti-HLA antibodies were studied by cytotoxicity crossmatching (CTXM) and flow cytometry crossmatching (FCXM) in 117 kidney transplant candidates; the same study was carried out in 33 cadaver-donor kidney recipients, during the first 3 post-transplant months, for which donor cells were available. Pre-transport evaluation showed that 82.9% of subjects were CTXM negative/FCXM negative, 6.8% of patients were positive in both tests, and 10.3% were CTXM negative/FCCM positive. Post-transplant monitoring for donor-specific antibodies (Abs-DS) showed that nine recipients (27.3%) were FCXM positive; six of them were IgG+ and three IgM+. In comparing these results with the clinical course, a significant association between FCXM IgG+ and rejection episodes was observed (P < 0.01).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0934-0874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S676-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14621907-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:14621907-Flow Cytometry,
pubmed-meshheading:14621907-Histocompatibility Testing,
pubmed-meshheading:14621907-Humans,
pubmed-meshheading:14621907-Immunoglobulin G,
pubmed-meshheading:14621907-Immunoglobulin M,
pubmed-meshheading:14621907-Isoantibodies,
pubmed-meshheading:14621907-Kidney Transplantation,
pubmed-meshheading:14621907-Monitoring, Immunologic,
pubmed-meshheading:14621907-Retrospective Studies,
pubmed-meshheading:14621907-Time Factors
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pubmed:year |
1992
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pubmed:articleTitle |
Kidney transplant monitoring by anti donor specific antibodies.
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pubmed:affiliation |
Clinica Chirurgica-II University of Rome, Rome, Italy.
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pubmed:publicationType |
Journal Article
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