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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-1-16
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pubmed:abstractText |
The renin angiotensin system is emerging as a potential therapeutic target for diabetic retinopathy. This study examines the effects of angiotensin-converting-enzyme inhibition by captopril and angiotensin AT(1) receptor antagonism using candesartan-cilexetil on retinal blood flow and acetylcholine-stimulated vasodilatation in normotensive diabetic rats.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0012-186X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-23
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14618237-Acetylcholine,
pubmed-meshheading:14618237-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:14618237-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:14618237-Animals,
pubmed-meshheading:14618237-Antihypertensive Agents,
pubmed-meshheading:14618237-Benzimidazoles,
pubmed-meshheading:14618237-Biphenyl Compounds,
pubmed-meshheading:14618237-Captopril,
pubmed-meshheading:14618237-Diabetes Mellitus, Experimental,
pubmed-meshheading:14618237-Fluorescein Angiography,
pubmed-meshheading:14618237-Hemodynamics,
pubmed-meshheading:14618237-Male,
pubmed-meshheading:14618237-Rats,
pubmed-meshheading:14618237-Rats, Sprague-Dawley,
pubmed-meshheading:14618237-Regional Blood Flow,
pubmed-meshheading:14618237-Retinal Vessels,
pubmed-meshheading:14618237-Tetrazoles,
pubmed-meshheading:14618237-Vasodilation
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pubmed:year |
2004
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pubmed:articleTitle |
Angiotensin AT(1) receptor antagonism normalizes retinal blood flow and acetylcholine-induced vasodilatation in normotensive diabetic rats.
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pubmed:affiliation |
Research Division and Beetham Eye Institute, Joslin Diabetes Center and Harvard Medical School, One Joslin Place, Boston, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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