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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-11-17
pubmed:abstractText
Few studies have focused on the clinical, neurophysiological and prognostic features of adult epileptic patients with malformation of cortical development. We reviewed the clinical data of a series of sixty adult epileptic patients with different types of malformation of cortical development, who had been followed at the Epilepsy Centre of the Department of Neurological Sciences of the University of Bologna, with particular attention to age at seizure onset, mental retardation, response to therapy, and EEG features. The heterogeneity of our population, especially when divided into the different groups of malformation of cortical development, precluded any general conclusions, but we stress the following aspects: 1). epilepsy due to malformation of cortical development may begin in adolescents and young adults; 2). epileptic seizures with clinical and polygraphic features of infantile spasms may persist into adulthood; 3). complex cortical malformation is not necessarily associated with severe epileptic encephalopathy. In periventricular nodular heterotopias, the largest in our series (nine patients), age at onset of seizures, response to therapy and mental deterioration differed according to the presence of nodules confined to the ventricular wall ('pure' form) or periventricular nodules associated with other cerebral cortical malformations ('plus' form).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1294-9361
pubmed:author
pubmed:copyrightInfo
Copyright John Libbey Eurotext 2003.
pubmed:issnType
Print
pubmed:volume
5 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S85-90
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Malformation of cortical development in adult patients.
pubmed:affiliation
Department of Neurological Sciences, University of Bologna, Italy. tinuper@neuro.unibo.it
pubmed:publicationType
Journal Article, Case Reports