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pubmed-article:14617198pubmed:abstractTextA cardinal feature of the adaptive immune response is its ability to generate long-lived populations of memory T lymphocytes. Memory T cells are specific to the antigen encountered during the primary immune response and react rapidly and vigorously upon re-encounter with the same antigen. Memory T cells that recognize microbial antigens provide the organism with long-lasting protection against potentially fatal infections. On the other hand, memory T cells that recognize donor alloantigens can jeopardize the survival of life-saving organ transplants. We review here the immunobiology of memory T cells and describe their role in the rejection of solid organ allografts.lld:pubmed
pubmed-article:14617198pubmed:languageenglld:pubmed
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pubmed-article:14617198pubmed:authorpubmed-author:ValujskikhAnn...lld:pubmed
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pubmed-article:14617198pubmed:volume196lld:pubmed
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pubmed-article:14617198pubmed:pagination65-74lld:pubmed
pubmed-article:14617198pubmed:dateRevised2005-11-16lld:pubmed
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pubmed-article:14617198pubmed:year2003lld:pubmed
pubmed-article:14617198pubmed:articleTitleIn remembrance of things past: memory T cells and transplant rejection.lld:pubmed
pubmed-article:14617198pubmed:affiliationDepartment of Immunology, The Cleveland Clinic Foundation, 9500 Euclid Avenue NB30, Cleveland, OH 44195, USA. valujsa@ccf.orglld:pubmed
pubmed-article:14617198pubmed:publicationTypeJournal Articlelld:pubmed
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