Source:http://linkedlifedata.com/resource/pubmed/id/14617198
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2003-11-17
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pubmed:abstractText |
A cardinal feature of the adaptive immune response is its ability to generate long-lived populations of memory T lymphocytes. Memory T cells are specific to the antigen encountered during the primary immune response and react rapidly and vigorously upon re-encounter with the same antigen. Memory T cells that recognize microbial antigens provide the organism with long-lasting protection against potentially fatal infections. On the other hand, memory T cells that recognize donor alloantigens can jeopardize the survival of life-saving organ transplants. We review here the immunobiology of memory T cells and describe their role in the rejection of solid organ allografts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0105-2896
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
196
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
65-74
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading | |
pubmed:year |
2003
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pubmed:articleTitle |
In remembrance of things past: memory T cells and transplant rejection.
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pubmed:affiliation |
Department of Immunology, The Cleveland Clinic Foundation, 9500 Euclid Avenue NB30, Cleveland, OH 44195, USA. valujsa@ccf.org
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pubmed:publicationType |
Journal Article,
Review
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