Source:http://linkedlifedata.com/resource/pubmed/id/14615251
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2003-11-17
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pubmed:abstractText |
Adequate acute treatment of the deeply burned hand and any subsequent reconstructive procedures may be hampered by the lack of sufficient suitable graft material and the risks of donor site morbidity and scarring. This investigation was designed to determine the feasibility of treating deep hand burns using a dermal regeneration template. Patients with deep hand burns underwent either acute treatment or reconstructive procedures with Integra dermal regeneration template. Wound sites were first grafted with the dermal regeneration template, and then 2-3 weeks later after neodermis formation the silicone layer of the Integra was removed and a very thin split-thickness epidermal autograft placed. Acute grafting was performed on 15 hands in 11 patients and reconstructive surgery on 14 hands in 11 patients. Median follow-up was 12 months. Integra take was 100% on all treated hands. After acute grafting the wound site skin was flexible and supple and did not adhere to the deeper layers, thus permitting free articular and functional movement. Cosmetic results of acute surgery were judged satisfactory by both patients and surgeons. After reconstructive procedures, significant improvements were achieved in cosmetic status, based on Vancouver Scar Scale (p=0.0002), and in three measures of function, namely, thumb opposition score (p=0.0005), fingertip-to-palm distance (p=0.0039) and prehensile score (p=0.0039). Favourable cosmetic and functional outcomes were consistently attained using a synthetic dermal regeneration template for treatment of deep hand burns either by acute grafting or reconstructive surgery.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0007-1226
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
764-74
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:14615251-Adolescent,
pubmed-meshheading:14615251-Adult,
pubmed-meshheading:14615251-Aged,
pubmed-meshheading:14615251-Biocompatible Materials,
pubmed-meshheading:14615251-Burns,
pubmed-meshheading:14615251-Child,
pubmed-meshheading:14615251-Chondroitin Sulfates,
pubmed-meshheading:14615251-Collagen,
pubmed-meshheading:14615251-Female,
pubmed-meshheading:14615251-Graft Survival,
pubmed-meshheading:14615251-Hand Injuries,
pubmed-meshheading:14615251-Humans,
pubmed-meshheading:14615251-Male,
pubmed-meshheading:14615251-Middle Aged,
pubmed-meshheading:14615251-Reconstructive Surgical Procedures,
pubmed-meshheading:14615251-Skin, Artificial,
pubmed-meshheading:14615251-Skin Transplantation,
pubmed-meshheading:14615251-Treatment Outcome,
pubmed-meshheading:14615251-Wound Healing
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pubmed:year |
2003
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pubmed:articleTitle |
Dermal regeneration template for deep hand burns: clinical utility for both early grafting and reconstructive surgery.
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pubmed:affiliation |
The Service des Brûlés, Hôpital Léon Bérard, Hyeres, Cedex 83400, France. eric.dantzer@wanadoo.fr
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pubmed:publicationType |
Journal Article
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