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pubmed-article:14614603pubmed:abstractTextGlycyrrhizin (GL), an aqueous extract of licorice root, is known to have various immune-modulating and biological response-modifier activities. GL is used in patients with hepatitis to reduce the activity of liver inflammation; however, the mechanism underlying the anti-inflammatory activity of GL is poorly understood. As antigen-presenting dendritic cells (DC) in the tissue play a major role in the regulation of the inflammatory mucosal milieu during tissue inflammation, we studied whether the function of liver DC was altered by GL therapy in a murine model of concanavalin-A (con A)-induced hepatitis.lld:pubmed
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pubmed-article:14614603pubmed:articleTitleGlycyrrhizin enhances interleukin-10 production by liver dendritic cells in mice with hepatitis.lld:pubmed
pubmed-article:14614603pubmed:affiliationThird Department of Internal Medicine, Ehime University School of Medicine, 791-0295, Ehime, Shigenobu-cho, Japan.lld:pubmed
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