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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-11-17
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pubmed:abstractText |
Glycyrrhizin (GL), an aqueous extract of licorice root, is known to have various immune-modulating and biological response-modifier activities. GL is used in patients with hepatitis to reduce the activity of liver inflammation; however, the mechanism underlying the anti-inflammatory activity of GL is poorly understood. As antigen-presenting dendritic cells (DC) in the tissue play a major role in the regulation of the inflammatory mucosal milieu during tissue inflammation, we studied whether the function of liver DC was altered by GL therapy in a murine model of concanavalin-A (con A)-induced hepatitis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0944-1174
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
962-7
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:14614603-Alanine Transaminase,
pubmed-meshheading:14614603-Animals,
pubmed-meshheading:14614603-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:14614603-Biological Markers,
pubmed-meshheading:14614603-Concanavalin A,
pubmed-meshheading:14614603-Dendritic Cells,
pubmed-meshheading:14614603-Disease Models, Animal,
pubmed-meshheading:14614603-Dose-Response Relationship, Drug,
pubmed-meshheading:14614603-Genes, MHC Class II,
pubmed-meshheading:14614603-Glycyrrhizic Acid,
pubmed-meshheading:14614603-Hepatitis,
pubmed-meshheading:14614603-Injections, Intraperitoneal,
pubmed-meshheading:14614603-Interleukin-10,
pubmed-meshheading:14614603-Interleukin-12,
pubmed-meshheading:14614603-Liver,
pubmed-meshheading:14614603-Male,
pubmed-meshheading:14614603-Mice,
pubmed-meshheading:14614603-Mice, Inbred C57BL,
pubmed-meshheading:14614603-Phenotype,
pubmed-meshheading:14614603-Sodium Chloride,
pubmed-meshheading:14614603-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:14614603-Time Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Glycyrrhizin enhances interleukin-10 production by liver dendritic cells in mice with hepatitis.
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pubmed:affiliation |
Third Department of Internal Medicine, Ehime University School of Medicine, 791-0295, Ehime, Shigenobu-cho, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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