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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-11-17
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pubmed:abstractText |
Clinically, the effect of chronic hypoxia (CH) in the pulmonary circulation alternates between phases of pulmonary artery hypertension (CH-PAHT) and normoxic normotensive remission (N-RE). Little information is available on the role of calcium-sensitive potassium channels (BK(Ca)) in both CH-PAHT and N-RE phases. In the present study, we investigated the effects of both CH and N-RE on BK(Ca) channels activity and their consequences on hypoxic pulmonary vasoconstriction (HPV).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
326-36
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14613862-Animals,
pubmed-meshheading:14613862-Anoxia,
pubmed-meshheading:14613862-Blotting, Western,
pubmed-meshheading:14613862-Calcium,
pubmed-meshheading:14613862-Hypertension, Pulmonary,
pubmed-meshheading:14613862-Male,
pubmed-meshheading:14613862-Muscle, Smooth, Vascular,
pubmed-meshheading:14613862-Patch-Clamp Techniques,
pubmed-meshheading:14613862-Peptides,
pubmed-meshheading:14613862-Potassium Channel Blockers,
pubmed-meshheading:14613862-Potassium Channels, Calcium-Activated,
pubmed-meshheading:14613862-Pulmonary Artery,
pubmed-meshheading:14613862-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:14613862-RNA, Messenger,
pubmed-meshheading:14613862-Rats,
pubmed-meshheading:14613862-Rats, Wistar,
pubmed-meshheading:14613862-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:14613862-Vasodilation
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pubmed:year |
2003
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pubmed:articleTitle |
Role of Ca(2+)-sensitive K(+) channels in the remission phase of pulmonary hypertension in chronic obstructive pulmonary diseases.
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pubmed:affiliation |
INSERM (EMI 0356), Université Bordeaux 2, 146 rue Léo-Saignat, 33076, Bordeaux, France. sebastienbonnet@lpcr.u-bordeaux2.fr
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
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