Source:http://linkedlifedata.com/resource/pubmed/id/14611894
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2003-11-12
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pubmed:abstractText |
Among strategies to combat malaria, the search for new antimalarial drugs appears to be a priority. Sheering for new antimalarial activities, four plants of the traditional medicine of Burkina Faso: Combretum micranthum, Khaya senegalensis, Pterocarpus erinaceus and Sida acuta, were tested in vitro on fresh clinical isolates of Plasmodium falciparum. The screening showed that Sida acuta has a significant activity (IC50 < 5 microg/ml), and Pterocarpus erinaceus has a moderate activity (5 microg/ml < IC50 < 50 microg/ml). Further chemical screening showed that the activity of the most active plant, Sida acuta, was related to its alkaloid contents.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0378-8741
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
291-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14611894-Animals,
pubmed-meshheading:14611894-Antimalarials,
pubmed-meshheading:14611894-Cells, Cultured,
pubmed-meshheading:14611894-Combretum,
pubmed-meshheading:14611894-Erythrocytes,
pubmed-meshheading:14611894-Humans,
pubmed-meshheading:14611894-Malvaceae,
pubmed-meshheading:14611894-Medicine, African Traditional,
pubmed-meshheading:14611894-Meliaceae,
pubmed-meshheading:14611894-Parasitic Sensitivity Tests,
pubmed-meshheading:14611894-Phytotherapy,
pubmed-meshheading:14611894-Plant Extracts,
pubmed-meshheading:14611894-Plant Structures,
pubmed-meshheading:14611894-Plasmodium falciparum,
pubmed-meshheading:14611894-Pterocarpus
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pubmed:year |
2003
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pubmed:articleTitle |
Antimalarial activity of Sida acuta Burm. f. (Malvaceae) and Pterocarpus erinaceus Poir. (Fabaceae).
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pubmed:affiliation |
Université de Ouagadougou, Centre de Recherche en Sciences Biologiques, Alimentaires et Nutritionnelles, Laboratoire de Biochimie, 03 BP 7131 Ouagadougou 03, Burkina Faso.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't
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