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pubmed-article:14611853pubmed:abstractTextA series of compounds containing an N-(4'-substituted-3'-nitrophenyl)sydnone moiety with potential antitumor activity was prepared based on active analogues. The rationale behind the design of these compounds is presented along with the 4-step synthetic route to the derivatives in the 4'-position of the phenyl sydnone framework. Out of the six novel compounds, the 4'-fluoro derivative has an improved activity against all three cell lines as compared to the earlier leads.lld:pubmed
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pubmed-article:14611853pubmed:articleTitleSynthesis and biological evaluation of a novel phenyl substituted sydnone series as potential antitumor agents.lld:pubmed
pubmed-article:14611853pubmed:affiliationDepartment of Chemistry and Biochemistry, University of the Sciences in Philadelphia, PA 19104, USA.lld:pubmed
pubmed-article:14611853pubmed:publicationTypeJournal Articlelld:pubmed
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