The septins are guanine-nucleotide binding proteins that mostly form filaments. They are important in cytokinesis and also have roles in sporulation in yeasts and embryonic development and in the nervous system in animals.
Biochemistry and Cell Biology Unit, HMRO, Kyoto University Graduate School of Medicine and PRESTO, Japan Science & Technology Agency, Yoshida Konoe, Sakyo, Kyoto 606-8501, Japan. mkinoshita@hmro.med.kyoto-u.ac.jp