Source:http://linkedlifedata.com/resource/pubmed/id/14609125
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2003-11-11
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pubmed:abstractText |
Two known farnesylacetone derivatives (1 and 2) were isolated from the Korean brown alga Sargassum sagamianum off Jeju Island, Korea. Compounds 1 and 2 were identified as (5E,10Z)-6,10,14-trimethylpentadeca-5,10-dien-2,12-dione and (5E,9E,13E)-6,10,4-trimethyl-pentadeca-5,9,13-trien-2,12-dione, respectively, by comparison with the literature data. Compounds 1 and 2 showed moderate acetylcholinesterase and butyrylcholinesterase inhibitory activities with IC50 values of 65.0 approximately 48.0 and 34.0 approximately 23.0 microM, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Butyrylcholinesterase,
http://linkedlifedata.com/resource/pubmed/chemical/Cholinesterase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Ketones,
http://linkedlifedata.com/resource/pubmed/chemical/Terpenes,
http://linkedlifedata.com/resource/pubmed/chemical/farnesylacetone
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0253-6269
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
796-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading | |
pubmed:year |
2003
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pubmed:articleTitle |
Cholinesterase inhibitory activity of two farnesylacetone derivatives from the brown alga Sargassum sagamianum.
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pubmed:affiliation |
Regional Research Center, Department of Chemical Technology, Hanbat National University, 16-1 Dukmyung-dong, Yusung-gu, Daejon 305-719, Korea.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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